priones

priones

Small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc; the cellular isoform is PrPC. The primary amino acid sequence of the two isoforms is identical. Among diseases caused by prions are scrapie, bovine spongiform encephalopathy, and Creuzfeldt-Jakob Syndrome.

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antihelmínticos

농업; 일반 농업

Agents destructive to parasitic worms. They are used therapeutically in the treatment of infestation with parasitic worms of the helminth class, in humans and animal.

antígenos de superficie

농업; 일반 농업

Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls.

antígenos de neoplasias

농업; 일반 농업

Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral ...

antígenos de histocompatibilidad

농업; 일반 농업

A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They ...

antígeno nuclear de célula proliferativa

농업; 일반 농업

Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the ...