Cardiovascular death includes death resulting from an acute myocardial infarction (MI), sudden cardiac death, death due to heart failure (HF), death due to stroke, death due to cardiovascular (CV) procedures, death due to CV hemorrhage, and death due to other CV causes. Classifying CV mortality more specifically (MI, sudden death etc.) is usually not needed for outcome trials. However, such classification is difficult because the classifications refer both to underlying cause (e.g., acute MI) and to mode of death (sudden/arrhythmic, progression of HF), and they overlap substantially. The following definitions can, however, be used if desired.